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Biological Safety

The development of a university biological safety program is undertaken for essentially the same reasons as you would develop any safety program.  Protection of the laboratory personnel and the environment is critical to all research and classroom activities involving biological agents.  Increasing awareness and knowledge of biosafety issues and providing applicable training opportunities will develop and maintain safe work practices and promote exemplary laboratory operations. 


The biosafety program at CMU has been designed to comply with federal, state and local regulations. Although aseptic techniques have long been established, the administration of biosafety programs are evolving along with cutting edge molecular techniques and protocols involving recombinant DNA technology.  Institutional policies must be risk based, carefully assessed, and critically reviewed on a case-by-case basis.  Principal Investigators must work closely with biosafety professionals to provide key information for novel research projects and to monitor changes that could potentially increase the risks.  After the biological risks have been evaluated, approval is granted by the CMU Institutional Biosafety Committee (IBC).  Composed of diverse, knowledgeable and interested members within the university and surrounding community, the IBC members collectively evaluate the research to be sure the work can be conducted in the safest manner possible.


Content below taken from BMBL, 6th edition.

Barriers and Biological Safety Cabinets

Primary Containment for Biohazards: Selection, Installation and Use of Biological Safety Cabinets​

Biosafety information

Commonly used acronyms

    ABSL: Animal Biosafety Level

    APHL: Association of Public Health Laboratories

    APHIS: Animal and Plant Health Inspection Service

    BBP: Blood Borne Pathogens

    BMBL: Biosafety in Microbiological and Biomedical Laboratories

    BSAT: Biological Select Agents and Toxins

    BSC: Biosafety Cabinet

    BSL: Biosafety Level

    BSO: Biological Safety Officer

    BPRP: Biological Personnel Reliability Program

    CDC: Centers for Disease Control and Prevention

    CFR: Code of Federal Regulations

    DEFRA: Department of Environment, Food, and Rural Affairs

    DGR: Dangerous Goods Regulations

    DHS: Department of Homeland Security

    DHHS: Department of Health and Human Services

    DOD: Department of Defense

    DOE: Department of Energy

    DOJ: Department of Justice

    DOS: Department of State

    DSAT: Division of Select Agents and Toxins

    FBI: Federal Bureau of Investigation

    FDA: Food and Drug Administration

    GMO: Genetically Modified Organism

    HHS: Department of Health and Human Services

    HSE: Health and Safety Executive

    IACUC: Institutional Animal Care and Use Committee

    IATA: International Air Transport Association

    IBC: Institutional Biosafety Committee

    IES: Investigative and Enforcement Services

    LRN: Laboratory Response Network

    MIOSHA: Michigan Occupation Health and Safety Administration

    MMWRA: Michigan Medical Waste Regulatory Act

    NBL: National Biocontainment Laboratories

    NIAID: National Institute of Allergy and Infectious Diseases

    NIH: National Institutes of Health

    NSABB: National Science Advisory Board for Biosecurity

    NSF: National Sanitation Foundation

    OBA Office of Biotechnology Activity

    OIG Office of Inspector General

    OPIM Other Potentially Infectious Material

    ORSP Office of Research and Sponsored Programs

    OSHA Occupational Safety and Health Administration

    PBSL Plant Biosafety Level

    PPE Personal Protective Equipment

    PI Principal Investigator

    RBL: Regional Biocontainment Laboratory

    RG: Risk Group

    RM/EHS: Risk Management/Environmental Health and Safety

    rDNA: Recombinant Deoxyribonucleic Acid

    SAPO: Specified Animal Pathogen Order

    TAMU: Texas A & M University

    USAMRIID: U.S. Army Medical Research Institute for Infectious Diseases

    USDA: United States Department of Agriculture

    WHO: World Health Organization