Lee, Choon
Professor
FACULTY
More about Choon Lee
Publications & Presentations
- Lee, C.Y.; Sharma, A.; Cheong, J.E.; Nelson, J.E. Synthesis and antioxidant properties of dendritic polyphenols. Bioorg. Med. Chem. Lett. 2009, 19(22), 6326-6330.
- Lee, C.Y.; Ki, D.W.; Sharma, A. Method for amine-amine attachment in nanodevice preparation. J. Mater. Sci. 2009, volume 44 (12), 3179-3185.
- Stuart, A.; McCallum, M.M.; Fan, D.; LeCaptain, D.J.; Lee, C.Y.; Mohanty, D.K. Poly(vinyl chloride) plasticized with succinate esters- Synthesis and characterization. Polym. Bull. (In press). Dendritic nano-antioxidants, US Provisional Patent No: 61/164,041, 2009.
- Desai, A.; Lee, C.; Sharma, L.; Sharma, A. Lysozyme refolding with cyclodextrins: Structure activity relationship. Biochimie, 2006, 88, 1435-1445.
- Hanson, R.N.; Lee, C.Y.; Friel, C. "Novel steroidal anti-estrogens and anti-androgens and uses thereof". 2006, Patent No: 7,041,839.
- Hanson, R.N.; Lee, C.Y.; Friel, C.; Dillis, R.; Hughes, A.; DeSombre, E. Synthesis and evaluation of 17α-20E-21-(4-substituted phenyl)-19-norpregna-1,3,5(10),20-tetraene-3,17β-diols as probes for the estrogen receptor α hormone binding domain. J. Med. Chem. 2003, 46, 2865-2876.
- Hanson, R.N.; Lee, C.Y.; DeSombre, E.; Hughes, A. Evaluation of 17a-E-(trifluoromethyl phenyl) vinyl estradiols as novel estrogen receptor ligands. Steroids, 2003, 68(2), 143-148.
- Sebag, A.; Hanson, R.N.; Forsyth, D.; Lee, C.Y. Conformational studies of novel estrogen receptor ligands by 1D and 2D NMR spectroscopy and computational methods. Magn. Reson. Chem. 2003, 41, 246-252.
- Lee, C.Y.; Hanson, R.N. Solid Phase Synthesis of 17a-E/Z-(X-phenyl)-vinyl estradiols using the Stille coupling reaction. Tetrahedron, 2000, 56, 1623-1629.
Education
- Ph.D., Biomedical Sciences, concentration in Medicinal Chemistry, Northeastern University, 2000
- M.S., Biomedical Sciences, concentration in Medicinal Chemistry, Northeastern University, 1997
Research Interests
- Investigation of anti-cancer agents
- Synthesis of antioxidant dendrimers for biological applications
Membership in Professional Organizations
- American Chemical Society
Courses Taught
- Organic Chemistry I and II
- Intermediate Organic Chemistry
- Organic Reactions and Synthesis