Conway, Michael
Ph.D.
Biography
Michael James Conway, Ph.D., is a tenured professor of microbiology in the Foundational Sciences Discipline at Central Michigan University College of Medicine. He holds a Bachelor of Science in microbiology and chemistry from Northern Michigan University and earned his doctorate in microbiology and immunology from the Pennsylvania State University College of Medicine under the mentorship of Dr. Craig Meyers. He completed his postdoctoral fellowship at Yale University School of Medicine, where he worked with Dr. Erol Fikrig in the Department of Internal Medicine Infectious Disease. Dr. Conway's research is focused on virology, vector-borne diseases, and virus-vector-host interactions, with a particular interest in flaviviruses such as dengue and West Nile virus. His work includes characterizing the roles of mosquito saliva proteins, midgut proteins, host lipids, and trehalose in mosquito biology and virus transmission. The Conway lab also performs molecular surveillance of SARS-CoV-2, RSV, norovirus, and influenza virus as part of the Michigan Network for Environmental Health & Technology (MiNET).
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Publications & Presentations
Conway M.J. (2023). Targeting Aedes aegypti Metabolism with Next Generation Insecticides Viruses.
Marten A. D. (2022). Chronic depletion of vertebrate lipids in Aedes aegypti cells promotes de novo lipid synthesis and supports dengue replication PLoS Neglected Tropical Diseases.
Michael J. Conway (2021). Type I hypersensitivity promotes Aedes aegypti blood feeding Scientific Reports.
Abeer Gharaibeh, Richard H. Smith, Michael J. Conway (2021). Reducing Spread of Infections with a Photocatalytic Reactor-Potential Applications in Control of Hospital Staphylococcus aureus and Clostridioides difficile Infections and Inactivation of RNA Viruses Infectious Disease Reports.
Michael J. Conway (2020). Extracellular vesicles restrict flavivirus fusion in Aedes aegypti cells Virology.
Michael J. Conway (2020). Validamycin A delays development and prevents flight in Aedes aegypti J Med Entomol.
Michael J. Conway (2020). Identification of coronavirus sequences in carp cDNA from Wuhan, China J Med Virol.
Conway, M.J (2020). Antibody responses against Anopheles darlingi immunogenic peptides in Plasmodium infected humans Frontiers in Cellular and Infection Microbiology.
Michael J. Conway (2019). Dengue virus reduces expression of low-density lipoprotein receptor-related protein 1 to facilitate replication in Aedes aegypti Sci Rep.
Conway, M.J. (2018). Rapid detection of Zika virus in urine samples and infected mosquitoes by reverse transcription-loop-mediated isothermal amplification Sci Rep.
Conway, M.J. (2018). Serosurvey of human antibodies recognizing Aedes aegypti D7 salivary proteins in Colombia Frontiers Public Health.
Conway, M.J (2018). Reverse transcriptase-loop-mediated isothermal amplification (RT-LAMP) assay for Zika virus and housekeeping genes in urine, serum, and mosquito samples J Vis Exp.
Michael J. Conway (2017). Low density lipoprotein inhibits flavivirus acquisition in Aedes aegypti Insect Mol Bio.
Conway, M.J. (2017). Zika virus induces astrocyte differentiation in neural stem cells J NeuroVirol.
Michael J. Conway (2017). New insight on dengue virus-induced thrombocytopenia. virulence Virulence.
Conway, M.J. (2016). Aedes aegypti D7 saliva protein binds and inhibits dengue virus infection PLoS Neg Trop Dis.
Michael J. Conway (2016). Insect specific flavivirus infection is restricted by mammalian innate immunity Virology.
Conway, M.J. (2016). A mosquito ubiquitin protein specifically targets dengue virus envelope protein for degradation and initiates cellular apoptosis during dengue infection of Aedes aegypti BBA.
Michael J. Conway (2016). Safe handling of West Nile virus in the insectary Methods Mol Biol.
Michael J. Conway (2016). Identification of a flavivirus sequence in a marine arthropod PLoS One.
Conway M.J. (2015). Cleavage of the HPV16 minor capsid protein L2 during virion morphogenesis ablates the requirement for cellular furin during de novo infection Viruses.
Conway, M.J (2015). Dengue virus infection of Aedes aegypti requires a cysteine rich venom protein PLoS Pathogens.
Conway, M.J (2014). Role of the vector in arbovirus transmission Ann. Rev. Virol..
Conway, M.J (2014). Roles for human papillomavirus type 16 L1 cysteine residues 161, 229, and 379 in genome encapsidation and capsid stability PLoS One.
Conway, M.J (2014). Adeno-associated virus type 2 infection of nude mouse human breast cancer xenograft induces necrotic death and inhibits tumor growth Cancer Biol Ther.
Conway, M.J., (2014). The susceptibility of high-risk human papillomavirus type 16 to clinical disinfectants J. Antimicrob. Chemother.
Conway, M.J (2014). Mosquito saliva serine protease enhances dissemination of dengue virus in the host. J. Virol.
Conway, M.J (2012). West Nile virus: biology, transmission, and human infection Clin. Microbiol. Rev.
Credentials, Certifications & Awards
Full Member of the Central Michigan University Academy of Medical Educators
Excellence in Teaching in Foundational Sciences Award Nominee
Dean's Travel Award
NIH/Roche Training Award
Central Michigan University Provost’s Award for Outstanding Research and Creative Activity
FRCCE Publication Cost Award
Founding Faculty Appreciation Award
Full Member in Sigma Xi Scientific Honor Society
CMED Excellence in Research Award
NCI Travel Grant
ASV Travl Award for the 31st Annual meeting
Dean's Award for Graduate Education
Class of 1979 Alumni Award
Education
B.S., Northern Michigan University
Membership in Professional Organizations
CMED Excellence in Research Award
Member of the International Papillomavirus Society
Faculty Research and Creative Endeavors Award
Central Michigan University Provost’s Award for Outstanding Research and Creative Activity
Full Member in Sigma Xi Scientific Honor Society
CMU Provost’s Award for Outstanding Research and Creative Activity Nominee
Full Member of the Central Michigan University Academy of Medical Educators
FRCE Publication Cost Award
CMED Excellence in Research Award Nominee
CMED Founding Faculty Appreciation Award
NIH/Roche Training Award for the 28th International Papillomavirus Conference
Pennsylvania State University College of Medicine Class of 1979 Alumni Award
ASV Travel Award for the 31st Annual Meeting for the American Society for Virology
NCI Travel Grant for the 2007 Small DNA Tumor Virus Meeting
Full member of the American Society for Virology
Pennsylvania State University College of Medicine Dean’s Award for Graduate Education
Member of the American Society of Tropical Medicine and Hygiene
American Society for Virology
NIH/Roche Training Award for the 27th International Papillomavirus Conference
PSU College of Medicine Dean’s Travel Award
American Society of Tropical Medicine and Hygiene